James McCluskey — ASN Events

Jim McCluskey

University of Melbourne, VIC, Australia

This delegate is presenting an abstract at this event.

Professor McCluskey's research involves understanding the structure, function and polymorphism of the major histocompatibility complex molecules that regulate adaptive immunity. He has an international reputation for his research in basic and clinical immunology and is recognised for his leadership in the field of HLA biology, HLA-linked drug hypersensitivities, CD1d recognition, and MAIT cell biology.

Jim McCluskey

University of Melbourne, VIC, Australia

MR1 is an endoplasmic reticulum-resident sensor of extracellular vitamin B metabolites (#30)

Identification and characterisation of a diverse repertoire of atypical MR1-restricted T cells (#21)

Public and private T cell receptor repertoires define NKT cell subsets with reactivity to CD1d-α-GalCer (#154)

Human MR1-restricted T cells expressing TRAV12-2 display ligand discrimination (#20)

MAIT cells become activated and depleted in macaque models of HIV/AIDS – implications for HIV pathogenesis and therapy (#50)

Immunological role of alternatively spliced isoforms of MR1 (#127)

MAIT cell infiltration in Helicobacter induced gastritis (#44)

Mucosal Associated Invariant T cells respond in vivo to riboflavin-derived ligands and co-stimulatory signals. (#46)

Identification of MR1 antigens using mass spectrometry (#105)

Identification of phenotypically and functionally heterogeneous mouse Mucosal Associated Invariant T cells using MR1 tetramers. (#116)

MR1-ligand induced apoptosis and functional impairment of mucosal associated invariant T (MAIT) cells in patients with rheumatoid arthritis and ankylosing spondylitis (#153)

Drugs/Drug analogues modulate MAIT cell function in an MR1-dependent manner (#98)

Recognition of Lipid Antigens by CD1-restricted T cells (#137)

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